Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death. They are named caspases due to their specific cysteine protease activity – a cysteine in its active site nucleophilically attacks and cleaves a target protein only after an aspartic acid r… Web据研究报道，在体外用人血灌注的猪器官和猪到非人灵长类动物（non-human primate，NHP）的异种移植中发现了NK细胞的浸润[10-13]，表明NK细胞参与了异种移植的排斥反应[22-23]。随后，人们对人NK细胞在异种移植中的作用机制进行了广泛的研究。本研究通过体外实验 ...

细胞焦亡在动脉粥样硬化发病机制中的研究进展

WebFactor associated suicide (Fas), factor associated suicide ligand (FasL), Bcl-2 homologous antagonist-killer protein (Bak), Cytochrome C, apoptotic peptidase activating factor 1 (Apaf-1), and cysteinyl aspartate specific proteinase (caspase)-3, -6, -7, -8, and -9 transcript expression was upregulated and B-cell lymphoma 2 (Bcl-2) transcript ... WebSmac/Diablo蛋白定位于线粒体，与连锁凋亡抑制蛋白家族结合后，抑制抗凋亡活性从而实现增强凋亡；cysteinyl aspartate specific proteinase-3基因 (caspase-3基因) 是在线粒体凋亡途径中执行最后步骤的凋亡基因[22-23]。 immoweb ham sur heure

冷应激对黑鲷组织损伤及细胞凋亡基因表达的影响_参考网

WebApr 10, 2024 · As for lamin B3(LMNB3), a germ cell-specific protein lacks the N-terminus and a part of the α-helical rod domain (coil1 and coil2) compared with its isomer LMNB2 ... Furthermore, LMNB2 can be directly or indirectly cleaved by cysteinyl aspartate specific proteinase (caspase) -3, -7, and -8, ... WebCaspase家族属于半胱氨酸蛋白酶，相当于线虫中的ced-3，具有高度同源性。这些蛋白酶均有以下特点：①总是在天冬氨酸之后切断底物，所以命名为Caspase（cysteine aspartate-specific protease）。②酶活性依赖于 … WebCysteinyl aspartate specific proteinase-3 (Caspase-3) is an important protein involved … immoweb havré