WebThe choice of phorbol 12-myristate 13-acetate differentiation protocol influences the response of THP-1 macrophages to a pro-inflammatory stimulus. The human monocytic … WebPhorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a reversible, highly potent activator of protein kinase C (PKC), including Group A and Group B isoforms (Blumberg). …
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WebPhorbol 12-myristate 13-acetate (PMA), also known as 12-O-tetradecanoylphorbol 13-acetate (TPA), is a phorbol ester and PKC activator. 1, 2, 3, 4, 5 It activates the PKC isoforms PKCα, -β, -γ, -δ, -ε, -η, and -θ but not PKCζ or -ι/λ. 2 PMA (1-10 ng/ml) induces NF-κB-dependent gene expression in a reporter assay. 3 It promotes the differentiation … WebMyristyl acetate Catalog NO.: B0001-130590 CAS NO.: 638-59-5 Brand: BOC Sciences Category Main Product Molecular Formula C16H32O2 Molecular Weight 256.42 Request another packsize? Click Bulk Order. BULK ORDER ADD TO CART FLASH CHECKOUT Specification Purity 95% Appearance Clear Colourless Oily Liquid Synonyms eagle grill and tavern hubbard ohio
PMA (Phorbol myristate acetate) NF-kB Activator
WebPHORBOL ESTERS INDUCE NA,K-ATPASE EXOCYTOSIS VIA PKC ACTIVATION Under certain experimental conditions (see below), direct stimulation of PKC by the phorbol ester phorbol 12-myristate 13-acetate (PMA) activates Na,K-ATPase ( 161, 320, 321 ). WebMar 25, 2024 · THP-1 cells were seeded into the upper insert of a 6-well Transwell apparatus (0.4 μm pore size, Corning, Lowell, MA, USA) and treated them with Phorbol myristyl acetate (PMA) (320 nM, P1585, Sigma-Aldrich, St. Louis, MO, … WebDescription. PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA … csir ugc net exam form